Cura te ipsum is a Latin expression, translated as "cure yourself," or colloquially, "physician, heal thyself." It reminds physicians to take care of themselves first, before caring for patients. It was said by Jesus to his disciple Luke (Luke 4:23), who was himself a healer or physician. NOTE: While Luke was a physician and a believer in Christ, Luke was not one of Jesus' original twelve disciples. This quote was a proverb - Jesus was responding to his hometown critics who did not believe in Him; He was particularly responding to their criticisms toward Him for not performing miracles in His own hometown.
While observing Benton, Reese notices he has benzodiazepine, a commonly used class of sedatives that includes Valium, Librium, and Rohypnol, which can be used as the date-rape drug commonly known as "roofies."
This episode highlights the dilemma Dr. Tillman faces: does someone bound by the Hippocratic Oath to "do no harm" really have a good reason to kill someone? At the same time, as Reese persuades her not to kill Benton, he confronts the possibility that there is an alternative to the killing he's been trained to do.
This episode also highlights the metamorphosis of Reese from a killer to a "healer". In the final scene with Benton, Reese has to decide how best to remove Benton from society, hence the image of the gun between his two hands: one is his killing hand, the other his healing hand. Reese relates to Benton's urge to hurt people and both express a desire to change, but who is being honest as well as the final outcome are left to the discretion of the viewer.
According to Jonah Nolan, the ending of the episode is deliberately ambiguous, leaving each viewer to decide whether Reese killed Benton or not.
Actress Linda Cardellini, who plays Dr. Megan Tillman, whose specialty is emergency medicine, previously played ER Nurse Samantha Taggart from Season 11 - 15 of the NBC series ER.
When Reese and Fusco confront the drug dealers at their apartment, there is a goal scored during a soccer match on the television. The famous "Goooooooooaaaaaaaaaaal" of Spanish-language sports commentator Andres Cantor, seen in the U.S. on NBC's Deportes Telemundo network, can be heard in the background.